diff --git a/changelogs/fragments/11812-sefcontext-matchpathcon-cache-flush.yml b/changelogs/fragments/11812-sefcontext-matchpathcon-cache-flush.yml
new file mode 100644
index 0000000000..942236daa8
--- /dev/null
+++ b/changelogs/fragments/11812-sefcontext-matchpathcon-cache-flush.yml
@@ -0,0 +1,6 @@
+bugfixes:
+  - sefcontext - flush the in-process ``matchpathcon`` cache after applying changes, so
+    subsequent tasks running in the same process (for example via the Mitogen connection
+    plugin) see the updated SELinux file context rules instead of stale cached data
+    (https://github.com/ansible-collections/community.general/issues/888,
+    https://github.com/ansible-collections/community.general/pull/11812).
diff --git a/plugins/modules/sefcontext.py b/plugins/modules/sefcontext.py
index 9014471cb0..1e64e21e8d 100644
--- a/plugins/modules/sefcontext.py
+++ b/plugins/modules/sefcontext.py
@@ -280,6 +280,10 @@ def semanage_fcontext_modify(module, result, target, ftype, setype, substitute,
     if module._diff and prepared_diff:
         result["diff"] = dict(prepared=prepared_diff)
 
+    if changed and not module.check_mode:
+        # Flush the in-process matchpathcon cache
+        selinux.matchpathcon_fini()
+
     module.exit_json(changed=changed, seuser=seuser, serange=serange, **result)
 
 
@@ -327,6 +331,10 @@ def semanage_fcontext_delete(module, result, target, ftype, setype, substitute,
     if module._diff and prepared_diff:
         result["diff"] = dict(prepared=prepared_diff)
 
+    if changed and not module.check_mode:
+        # Flush the in-process matchpathcon cache
+        selinux.matchpathcon_fini()
+
     module.exit_json(changed=changed, **result)